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KMID : 0384320070280080610
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Korean Journal of Family Medicine
2007 Volume.28 No. 8 p.610 ~ p.615
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The Validity of Michigan Neuropathy Screening Instrument as a Screening Test and Risk Factors for Diabetic Peripheral Neuropathy
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Do Hyun-Jin
Oh Seung-Won
Lym Youl-Lee
Choi Jae-Kyung
Joh Hee-Kyung
Kweon Hyuk-Jung
Cho Dong-Young
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Abstract
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Background: Diabetic neuropathy is a common complication of diabetes. Since neuropathy leads to ulceration and amputation, efforts to detect early and to elucidate its risk factors are ongoing. The goal of this study was to check the validity of Michigan neuropathy screening instrument (MNSI) as a screening test and its risk factors for diabetic neuropathy.
Methods: A total of 75 subjects with type II diabetes mellitus, who visited a university hospital, were investigated. We measured their duration of diabetes, height, weight, systolic blood pressure, diastolic blood pressure, fasting glucose, glycosylated hemoglobin, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, serum creatinine, and 24-h urine albumin. MNSI tested and electrophysiological test were performed.
Results: The sensitivity, specificity, positive predictive value, and negative predictive value of MNSI was 63.5%, 78.3%, 86.8%, and 48.6%, respectively. Statistically significant relationships were found between neuropathy and the duration of diabetes and total cholesterol.
Conclusion: MNSI seemed to be an appropriate screening test for diabetic neuropathy. More attention must be paid to the duration of diabetes and the total cholesterol of type 2 diabetic patients with peripheral neuropathy. (J Korean Acad Fam Med 2007;28:610-615)
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KEYWORD
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Michigan neuropathy screening instrument, diabetic neuropathy, risk factor
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